
Though he was only ever directly the teacher of the Sannin, generations of Konoha shinobi benefited from his wisdom during his lifetime. A disciple of the village's previous Hokage, Hiruzen was a powerful ninja, hailed as a "God of Shinobi". Hiruzen Sarutobi (猿飛ヒルゼン, Sarutobi Hiruzen) was the Third Hokage (三代目火影, Sandaime Hokage, Literally meaning: Third Fire Shadow) of Konohagakure.

After his brother's death, he would succeed the title of Second Hokage (二代目火影, Nidaime Hokage, Literally meaning: Second Fire Shadow). Throughout his lifetime, Tobirama would work tirelessly to achieve political stability and implement the institutions that made the village system work, thus ensuring Konoha's continuity and prosperity. Tobirama Senju (千手扉間, Senju Tobirama) was a member of the renowned Senju clan, who, together with his elder brother and the Uchiha clan, founded the first shinobi village: Konohagakure. Although he was not able to achieve peace during his lifetime, his legacy and vision for the world would continue to shape the village and the entire shinobi world even after his death. He would later become the First Hokage (初代火影, Shodai Hokage, Literally meaning: First or Founding Fire Shadow) of Konohagakure. Hashirama sought peace for the shinobi world, and to that end founded Konohagakure with his clan, his childhood friend and rival: Madara Uchiha and the Uchiha clan. He himself was hailed as the "God of Shinobi" for his unmatched ninja prowess. Hashirama Senju (千手柱間, Senju Hashirama) was a member of the famed Senju clan. The workload of Hokage can be quite formidable, and as such retired Hokage may continue to oversee certain sections of the village or, if not that, will advise the current Hokage on request.

Each Hokage typically lives according to the Will of Fire, a philosophy that holds that Konoha is a family and that the Hokage is chiefly responsible for protecting that family. The Hokage spends most of their time in the village, only travelling abroad for events of vital importance to Konoha. Hokage are responsible for most of the village's day-to-day affairs, such as assigning the village's ninja to missions or securing funding for the village's projects and personnel. The Hokage's office is located in the administrative section of the Academy. Once they assume the duties of Hokage, their face is carved into the Hokage Rock and they usually move in to the Hokage Residence. The new Hokage is granted a ceremonial haori on the occasion the same woman has embroidered the haori for all seven Hokage. The Hokage's inauguration is a major event in Konoha, with most of the village attending. If one of the Hokage's predecessors is still alive, they may return to office rather than select a new Hokage, as when the Third came out of retirement following the Fourth's death. This choice must then be approved by Konoha's jōnin. If they die or are otherwise incapacitated, the next Hokage is instead chosen by the daimyō of the Land of Fire with the advice of his committee, the Konoha Council, the Jōnin Commander and a representative of the Anbu.

The Hokage typically selects their successor. Despite this, all of the village's Hokage have traced back to Hashirama in some way: the Second was his brother the Third was his student the Fourth was a student of one of the Third's students the Fifth is his granddaughter and another student of the Third the Sixth was a student of the Fourth the Seventh is a student of the Sixth and the son of the Fourth. Madara feared that Hashirama's selection was the first step in making the Hokage office an extension of the Senju clan's authority, a fear Hashirama denied. He intended the title to be given to his co-founder, Madara Uchiha, but the village's population instead selected Hashirama as the First Hokage. The Hokage position was created shortly after the creation of Konoha by Hashirama Senju, one of the village's founders.
